Found 28 matching trials
Real-world Study of Local Therapy Changes During 1L Lorlatinib in Unresectable ALK+ NSCLC
N/AThis real-word study is designed to prospectively explore whether local tre...
Location
Multiple Locations
Temodar Plus Tyrosine Kinase Inhibitors for Progressive CNS Disease
PHASE1This trial is testing two novel combinations (temozolomide plus osimertinib...
Location
University of Colorado Hospital
A Study of Lorlatinib in ALK Inhibitor-Treated ALK-Positive NSCLC in China
PHASE2A Phase 2, multi center, open label, dual cohort study to evaluate the effi...
Location
Gaoxin Hospital of The First Affilated Hospital of Anhui Medical University
Lorlatinib in ALK Inhibitor Treated Unresectable Advanced/Recurrent ALK-Positive Non Small Cell Lung Cancer Patients in India
PHASE4Lorlatinib is a third-generation, oral, reversible, ATP-competitive, macroc...
Location
The Gujarat Cancer and Research Institute
A Study To Evaluate The Effect Of Rifampin On Pharmacokinetics Of PF-06463922 In Healthy Volunteers
PHASE1The purpose of this study is to estimate the effect of rifampin on the sing...
Location
Pfizer New Haven Clinical Research Unit
A Study of Lorlatinib in Combination With Ramucirumab in People With Lung Cancer
PHASE1This study will test the safety of the combination of ramucirumab and lorla...
Status
Active Not Recruiting
Location
Memorial Sloan Kettering Monmouth (All Protocol Activities)
Lorlatinib as Neoadjuvant Treatment in Stage IB-IIIB ALK-rearranged Non-Small Cell Lung Cancer
PHASE2This project was designed To explore the pathological complete response (pC...
Location
Multiple Locations
Analysis of the Effectiveness and Safety of Lorlatinib in Untreated ALK-Positive NSCLC Patients in a French Real-World Context
NAAnalysis of the Effectiveness and Safety of Lorlatinib in Untreated ALK-Pos...
NANT 2015-02: A Phase 1 Study of Lorlatinib (PF-06463922)
PHASE1Lorlatinib is a novel inhibitor across ALK variants, including those resist...
Location
Children's Hospital Los Angeles
A Study Of Lorlatinib Versus Crizotinib In First Line Treatment Of Patients With ALK-Positive NSCLC
PHASE3A phase 3 study to demonstrate whether lorlatinib given as monotherapy is s...
Status
Active Not Recruiting
Location
Florida Cancer Specialists